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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1930 1
1933 1
1938 2
1940 1
1942 1
1943 1
1950 1
1954 2
1961 1
1963 2
1965 1
1966 3
1968 3
1969 5
1970 2
1971 1
1972 1
1975 4
1976 6
1977 4
1978 6
1979 4
1980 6
1981 4
1982 8
1983 9
1984 7
1985 7
1986 7
1987 7
1988 11
1989 12
1990 26
1991 21
1992 20
1993 16
1994 21
1995 18
1996 27
1997 23
1998 23
1999 19
2000 34
2001 36
2002 37
2003 54
2004 47
2005 57
2006 67
2007 55
2008 62
2009 75
2010 85
2011 76
2012 72
2013 85
2014 128
2015 139
2016 140
2017 163
2018 120
2019 136
2020 132
2021 166
2022 149
2023 193
2024 79

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Search Results

2,450 results

Results by year

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Page 1
Autophagy-Independent Functions of the Autophagy Machinery.
Galluzzi L, Green DR. Galluzzi L, et al. Cell. 2019 Jun 13;177(7):1682-1699. doi: 10.1016/j.cell.2019.05.026. Cell. 2019. PMID: 31199916 Free PMC article. Review.
Macroautophagy (herein referred to as autophagy) is an evolutionary ancient mechanism that culminates with the lysosomal degradation of superfluous or potentially dangerous cytosolic entities. Over the past 2 decades, the molecular mechanisms underlying several vari …
Macroautophagy (herein referred to as autophagy) is an evolutionary ancient mechanism that culminates with the lysosomal degradation …
The Human Gut Microbiota: A Key Mediator of Osteoporosis and Osteogenesis.
Seely KD, Kotelko CA, Douglas H, Bealer B, Brooks AE. Seely KD, et al. Int J Mol Sci. 2021 Aug 31;22(17):9452. doi: 10.3390/ijms22179452. Int J Mol Sci. 2021. PMID: 34502371 Free PMC article. Review.
Studies have proposed various mechanisms of gut microbiome interaction with osteoclastogenesis and bone health, including micro-RNA, insulin-like growth factor 1, and immune system mediation. However, alterations to the gut microbiome secondary to pharmaceutical and surgic …
Studies have proposed various mechanisms of gut microbiome interaction with osteoclastogenesis and bone health, including micro-RNA, …
Eccentric Exercise: Physiological Characteristics and Acute Responses.
Douglas J, Pearson S, Ross A, McGuigan M. Douglas J, et al. Sports Med. 2017 Apr;47(4):663-675. doi: 10.1007/s40279-016-0624-8. Sports Med. 2017. PMID: 27638040 Review.
An eccentric contraction involves the active lengthening of muscle under an external load. The molecular and neural mechanisms underpinning eccentric contractions differ from those of concentric and isometric contractions and remain less understood. A number of molecular t …
An eccentric contraction involves the active lengthening of muscle under an external load. The molecular and neural mechanisms underp …
Endocrine Disrupting Chemicals, Hormone Receptors, and Acne Vulgaris: A Connecting Hypothesis.
Rao A, Douglas SC, Hall JM. Rao A, et al. Cells. 2021 Jun 9;10(6):1439. doi: 10.3390/cells10061439. Cells. 2021. PMID: 34207527 Free PMC article. Review.
The pathogenesis of acne involves several hormonal pathways, including androgens, insulin-like growth factor 1(IGF-1), estrogens, and corticosteroids. EDCs influence these pathways primarily through two mechanisms: altering endogenous hormone levels and interfering with ho …
The pathogenesis of acne involves several hormonal pathways, including androgens, insulin-like growth factor 1(IGF-1), estrogens, and cortic …
Bisphosphonate.
Ganesan K, Goyal A, Roane D. Ganesan K, et al. 2023 Jul 3. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. 2023 Jul 3. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 29262103 Free Books & Documents.
Their effectiveness in treating osteoporosis and other conditions is related to their ability to inhibit bone resorption. This activity will highlight the mechanism of action, adverse event profile, and other key factors (e.g., off-label uses, dosing, pharmacodynamics, pha …
Their effectiveness in treating osteoporosis and other conditions is related to their ability to inhibit bone resorption. This activity will …
Atomoxetine.
Fedder D, Patel H, Saadabadi A. Fedder D, et al. 2023 Mar 27. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. 2023 Mar 27. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 29630286 Free Books & Documents.
Although atomoxetine is only FDA-approved for treating ADHD, it is sometimes used off-label to treat adult patients with treatment-resistant depression. This activity outlines the indications, mechanism of action, administration, adverse effects, contraindications, and mon …
Although atomoxetine is only FDA-approved for treating ADHD, it is sometimes used off-label to treat adult patients with treatment-resistant …
Alzheimer's trials: A cul-de-sac with no end in sight.
Kurkinen M. Kurkinen M. Adv Clin Exp Med. 2021 Jul;30(7):653-654. doi: 10.17219/acem/139501. Adv Clin Exp Med. 2021. PMID: 34313409 Free article.
We don't understand Alzheimer, its origin and disease mechanisms. The absence of disease-modifying treatments for Alzheimer today is due to the amyloid hypothesis, a misguided hypothesis of Alzheimer's disease etiology, which has dominated Alzheimer research, drug developm …
We don't understand Alzheimer, its origin and disease mechanisms. The absence of disease-modifying treatments for Alzheimer today is …
Eating Disorders and Epigenetics.
Thaler L, Steiger H. Thaler L, et al. Adv Exp Med Biol. 2017;978:93-103. doi: 10.1007/978-3-319-53889-1_5. Adv Exp Med Biol. 2017. PMID: 28523542 Review.
The complex of symptoms that characterize EDs often arise through the activation of latent genetic potentials by environmental exposures, and epigenetic mechanisms are believed to link environmental exposures to gene expression. ...It then provides a background to the hypo …
The complex of symptoms that characterize EDs often arise through the activation of latent genetic potentials by environmental exposures, an …
Optical coherence tomography angiography in neuro-ophthalmology.
Douglas VP, Douglas KAA, Torun N. Douglas VP, et al. Curr Opin Ophthalmol. 2023 Jul 1;34(4):354-360. doi: 10.1097/ICU.0000000000000955. Epub 2023 Apr 18. Curr Opin Ophthalmol. 2023. PMID: 37070535 Review.
SUMMARY: Since its introduction, OCTA has emerged as an important imaging approach shedding light on unrevealed pathophysiological mechanisms of several ocular diseases. The use of OCTA as a biomarker in the field of neuro-ophthalmology has recently gained considerable att …
SUMMARY: Since its introduction, OCTA has emerged as an important imaging approach shedding light on unrevealed pathophysiological mechan …
Simple animal models for microbiome research.
Douglas AE. Douglas AE. Nat Rev Microbiol. 2019 Dec;17(12):764-775. doi: 10.1038/s41579-019-0242-1. Epub 2019 Aug 15. Nat Rev Microbiol. 2019. PMID: 31417197 Review.
The development of rational microbial therapies to alleviate chronic immunological, metabolic and neurobiological diseases requires an understanding of the processes underlying microbial community assembly and the mechanisms by which microorganisms influence host traits. F …
The development of rational microbial therapies to alleviate chronic immunological, metabolic and neurobiological diseases requires an under …
2,450 results